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Powder particles.
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Classical process.
Build-up of granulates from powder.
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Comparison.
Wet granulates are generally denser and more mechanically
stable particles than fluid bed granulates.
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Product advantages.
Fast build-up of granulate.
Compact and stable
structure.
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Grain sizes.
Between 0.1mm and 10mm possible depending upon the downstream sieve.
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Process Principles
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Wet granulation in a vertical granulator is the classical method for building
up granulates from powder. (-> Wet
Granulation in the vertical granulator)
In this process, powder is fed to
a product container and then moistened or sprayed with molten material in order
to increase the cohesive forces. The liquid can be water or an organic solvent,
if necessary with a binder. At the same time, the ingredients are mixed together
vigorously.
Denser granulates are formed than in the case of Agglomeration/Granulation in the fluid bed.
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Product characteristics |
Wet granulate
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Dust free
Good flow behaviour
Easy to dose
Good dispersibility
Good solubility
Highly suitable for making into tablets
Compact structure
Low hygroscopicity
High bulk density
Wide grain size distribution
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Manufacturing options
For this process, Glatt offers Vertical Granulators with batch sizes from
100g to 1t/batch. |
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